Inclusion & Exclusion Criteria

INCLUSION CRITERIA

General inclusion criteria:

  • AGE > 50 years

  • No history of supraventricular arrhythmia

  • Sinus rhythm at inclusion

  • CHADSVASc score > 2 in men (> 3 in female)

  • Written informed consent is obtained before any study-related assessment is performed

  • More than 3 specific criteria for inclusion

Specific criteria for inclusion:

  • Age > 65

  • Age > 75

  • BMI > 30

  • Heart failure with preserved LVEF (according to ESC GL for HF)

  • Ischemic stroke

  • Left atrial diameter > 45mm

  • Chronic obstructive pulmonary disease

  • Arterial hypertension

  • PR interval > 200ms

  • History of MI or (objective evidence of) chronic coronary syndrome

  • Peripheral artery disease

  • Thyroid disease


EXCLUSION CRITERIA

  • History of any supraventricular or ventricular arrhythmia (excluding premature contractions and 1st degree AV block)

  • Therapy with anticoagulants at the time of inclusion

  • Acute coronary syndrome less than one month prior to inclusion

  • History of cardiac surgery

  • Diabetes mellitus type 2

  • Reduced LVEF (<50%)

  • Acute or decompensated heart failure at the time of inclusion

  • Cardiomyopathy

  • Systemic inflammatory disease or acute inflammatory disease

  • Active malignancy

  • Alcoholism (≥ 8 drinks/week)

  • Renal Disease (Dialysis/ transplant/ CrCl < 1ml/s)

  • Liver disease (Cirrhosis/ transaminase > 3x ULT/ bilirubin > 2x ULT)

  • Severe or moderate mitral stenosis

  • Pregnancy